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1

Targeted Killing of Cancer Cells in Vivo and in Vitro with EGF-Directed Carbon Nanotube-Based Drug Delivery

Patel, Vyomesh, Gavard, Julie, Zhang, Guofeng, Sousa, Alioscka A., Masedunskas, Andrius, Leapman, Richard D., Weigert, Roberto, Gutkind, J. Silvio, Rusling, James F., Bhirde, Ashwin A.

Journal:

Year:

2009

Language:

english

File:

PDF, 2.88 MB

english, 2009

2

Virally Encoded GPCRs as Potential Therapeutic Targets

Gutkind, Silvio, Martin, Daniel

Journal:

Annual Review of Pharmacology

Year:

2012

Language:

english

File:

PDF, 1.18 MB

english, 2012

3

Engineered Mesenchymal Stem Cells with Enhanced Tropism and Paracrine Secretion of Cytokines and Growth Factors to Treat Traumatic Brain Injury

Wang, Zhe, Wang, Yu, Wang, Zhiyong, Gutkind, J. Silvio, Wang, Zhongliang, Wang, Fu, Lu, Jie, Niu, Gang, Teng, Gaojun, Chen, Xiaoyuan

Journal:

Year:

2015

Language:

english

File:

PDF, 2.33 MB

english, 2015

4

Detecting cancer metastasis and accompanying protein biomarkers at single cell levels using a 3D-printed microfluidic immunoarray

Sharafeldin, Mohamed, Chen, Tianqi, Ozkaya, Gulsum Ucak, Choudhary, Dharamainder, Molinolo, Alfredo A., Gutkind, J. Silvio, Rusling, James F.

Journal:

Biosensors and Bioelectronics

Year:

2021

File:

PDF, 18 KB

2021

5

Proteomic profiling of the cancer microenvironment by antibody arrays

Vladimir Knezevic, Chidchanok Leethanakul, Verena E. Bichsel, Jennifer M. Worth, Vinay V. Prabhu, J. Silvio Gutkind, Lance A. Liotta, Peter J. Munson, Emanuel F. Petricoin III, David B. Krizman

Journal:

Year:

2001

Language:

english

File:

PDF, 114 KB

english, 2001

6

The kaposi’s sarcoma associated herpesvirus: a model for viral oncogenesis

Akrit Sodhi, J. Silvio Gutkind, Silvia Montaner

Journal:

Clinical and Translational Oncology

Year:

2002

File:

PDF, 338 KB

2002

7

10.1038/35003235

Gu, Hua, Chiang, Yungping J., Kole, Hemanta K., Brown, Karen, Naramura, Mayumi, Fukuhara, Shigetomo, Hu, Ren-Ju, Jang, Ihn Kyung, Gutkind, J. Silvio, Shevach, Ethan

Journal:

Year:

2000

Language:

english

File:

PDF, 232 KB

english, 2000

8

10.1038/45822

Di Fiore, Pier Paolo, Scita, Giorgio, Nordstrom, Johan, Carbone, Roberta, Tenca, Pierluigi, Giardina, Giuseppina, Gutkind, Silvio, Bjarnegård, Mattias, Betsholtz, Christer

Journal:

Year:

1999

Language:

english

File:

PDF, 316 KB

english, 1999

9

Epidermal growth factor receptor is a co-receptor for adeno-associated virus serotype 6

Weller, Melodie L, Amornphimoltham, Panomwat, Schmidt, Michael, Wilson, Paul A, Gutkind, J Silvio, Chiorini, John A

Journal:

Nature Medicine

Year:

2010

Language:

english

File:

PDF, 407 KB

english, 2010

10

G-protein-coupled receptors and cancer

Dorsam, Robert T., Gutkind, J. Silvio

Journal:

Nature Reviews Cancer

Year:

2007

Language:

english

File:

PDF, 1.23 MB

english, 2007

11

The emerging mutational landscape of G proteins and G-protein-coupled receptors in cancer

O'Hayre, Morgan, Vázquez-Prado, José, Kufareva, Irina, Stawiski, Eric W., Handel, Tracy M., Seshagiri, Somasekar, Gutkind, J. Silvio

Journal:

Nature Reviews Cancer

Year:

2013

Language:

english

File:

PDF, 3.05 MB

english, 2013

12

A role for p38 MAPK in head and neck cancer cell growth and tumor-induced angiogenesis and lymphangiogenesis

Leelahavanichkul, Kantima, Amornphimoltham, Panomwat, Molinolo, Alfredo A., Basile, John R., Koontongkaew, Sittichai, Gutkind, J. Silvio

Journal:

Molecular Oncology

Year:

2014

Language:

english

File:

PDF, 4.04 MB

english, 2014

13

Fluorescent, Bioactive Protein Nanoparticles (Prodots) for Rapid, Improved Cellular Uptake

Deshapriya, Inoka K., Stromer, Bobbi S., Pattammattel, Ajith, Kim, Christina S., Iglesias-Bartolome, Ramiro, Gonzalez-Fajardo, Laura, Patel, Vyomesh, Gutkind, J. Silvio, Lu, Xiuling, Kumar, Challa V.

Journal:

Bioconjugate Chemistry

Year:

2015

Language:

english

File:

PDF, 5.15 MB

english, 2015

14

Polymeric Nanovehicle Regulated Spatiotemporal Real-Time Imaging of the Differentiation Dynamics of Transplanted Neural Stem Cells after Traumatic Brain Injury

Wang, Zhe, Wang, Yu, Wang, Zhiyong, Zhao, Jun, Gutkind, J. Silvio, Srivatsan, Avinash, Zhang, Guofeng, Liao, Hsien-Shun, Fu, Xiao, Jin, Albert, Tong, Xiao, Niu, Gang, Chen, Xiaoyuan

Journal:

Year:

2015

Language:

english

File:

PDF, 9.75 MB

english, 2015

15

An interplay between the p38 MAPK pathway and AUBPs regulates c-fos mRNA stability during mitogenic stimulation

Degese, Maria Sol, Tanos, Tamara, Naipauer, Julian, Gingerich, Tim, Chiappe, Diego, Echeverria, Pablo, LaMarre, Jonathan, Gutkind, J. Silvio, Coso, Omar A.

Journal:

Biochemical Journal

Year:

2015

Language:

english

File:

PDF, 1.63 MB

english, 2015

16

Unraveling the oral cancer lncRNAome: Identification of novel lncRNAs associated with malignant progression and HPV infection

Nohata, Nijiro, Abba, Martin C., Gutkind, J. Silvio

Journal:

Year:

2016

Language:

english

File:

PDF, 3.77 MB

english, 2016

17

Epidermal loss of Gαq confers a migratory and differentiation defect in keratinocytes

Doçi, Colleen L., Mikelis, Constantinos M., Callejas-Valera, Juan Luis, Hansen, Karina K., Molinolo, Alfredo A., Inoue, Asuka, Offermanns, Stefan, Gutkind, J. Silvio, McNeil, Paul

Journal:

Year:

2017

Language:

english

File:

PDF, 2.92 MB

english, 2017

18

Structure of the C-terminal guanine nucleotide exchange factor module of Trio in an autoinhibited conformation reveals its oncogenic potential

Bandekar, Sumit J., Arang, Nadia, Tully, Ena S., Tang, Brittany A., Barton, Brenna L., Li, Sheng, Gutkind, J. Silvio, Tesmer, John J. G.

Journal:

Science Signaling

Year:

2019

Language:

english

File:

PDF, 908 KB

english, 2019

19

Effect of activating and inactivating mutations of GS-and Gi2-alpha protein subunits on growth and differentiation of 3T3-L1 preadipocytes

Jan Oxholm Gordeladze, Kjerstin Elisabeth Høvik, John Jack Merendino, Sylvie Hermouet, Silvio Gutkind, Domenico Accili

Journal:

Journal of Cellular Biochemistry

Year:

1997

Language:

english

File:

PDF, 389 KB

english, 1997

20

Dual transduction signaling by a Xenopus muscarinic receptor: Adenylyl cyclase inhibition and MAP kinase activation

Luisa Herrera, María Victoria Hinrichs, Jorge Frías, Silvio Gutkind, Juan Olate

Journal:

Journal of Cellular Biochemistry

Year:

1997

Language:

english

File:

PDF, 118 KB

english, 1997

21

Probes for narcotic receptor mediated phenomena 22. (1) synthesis and characterization of optically pure [3H](+)-4-[(αR)-α-((2S, 5R)-4-propyl-2,5-dimethyl-1-piperazinyl)-3-methoxybenzyl]-N, N-diethylbenzamide, [3H]SNC 121, a novel high affinity and selective ligand for delta opioid receptors

Silvia N. Calderon, Craig M. Bertha, J. Silvio Gutkind, Heng Xu, John S. Partilla, Richard B. Rothman, Kenner C. Rice

Journal:

Journal of Labelled Compounds and Radiopharmaceuticals

Year:

1996

Language:

english

File:

PDF, 236 KB

english, 1996

22

Induction of apoptosis in head-and-neck squamous carcinoma cells by γ-irradiation and bleomycin is p53-independent

Vyomesh Patel, John F. Ensley, J. Silvio Gutkind, W. Andrew Yeudall

Journal:

International Journal of Cancer

Year:

2000

Language:

english

File:

PDF, 201 KB

english, 2000

23

Nanostructured Immunosensor for Attomolar Detection of Cancer Biomarker Interleukin-8 Using Massively Labeled Superparamagnetic Particles

Prof. Bernard S. Munge, Amy L. Coffey, Jaimee M. Doucette, Brian K. Somba, Ruchika Malhotra, Dr. Vyomesh Patel, Dr. J. Silvio Gutkind, Prof. James F. Rusling

Journal:

Angewandte Chemie

Year:

2011

Language:

english

File:

PDF, 554 KB

english, 2011

24

Nanostructured Immunosensor for Attomolar Detection of Cancer Biomarker Interleukin-8 Using Massively Labeled Superparamagnetic Particles

Prof. Bernard S. Munge, Amy L. Coffey, Jaimee M. Doucette, Brian K. Somba, Ruchika Malhotra, Dr. Vyomesh Patel, Dr. J. Silvio Gutkind, Prof. James F. Rusling

Journal:

Angewandte Chemie International Edition

Year:

2011

Language:

english

File:

PDF, 537 KB

english, 2011

25

A nonsynonymous single-nucleotide polymorphism in the PDZ-Rho guanine nucleotide exchange factor (Ser1416Gly) modulates the risk of lung cancer in Mexican Americans

Jian Gu, Xifeng Wu, Qiong Dong, Martin J. Romeo, Xin Lin, J. Silvio Gutkind, David M. Berman

Journal:

Year:

2006

Language:

english

File:

PDF, 99 KB

english, 2006

26

Meeting Report—The NIDCR 2nd Salivary Gland Tumor Meeting, November 2008

Dr. Adel K. El-Naggar, Dr. Frederic J. Kaye, Dr. Yasaman Shirazi, Dr. J. Silvio Gutkind, Dr. Arlene A. Forastiere

Journal:

Year:

2009

Language:

english

File:

PDF, 47 KB

english, 2009

27

Laminin-γ2 overexpression in head-and-neck squamous cell carcinoma

Vyomesh Patel, Kay Aldridge, John F. Ensley, Edward Odell, Andrea Boyd, Judith Jones, J. Silvio Gutkind, W. Andrew Yeudall

Journal:

International Journal of Cancer

Year:

2002

Language:

english

File:

PDF, 759 KB

english, 2002

28

Global gene expression profiles of human head and neck squamous carcinoma cell lines

Geoung A. Jeon, Ju-Seog Lee, Vyomesh Patel, J. Silvio Gutkind, Snorri S. Thorgeirsson, Eun Cheol Kim, In-Sun Chu, Panomwat Amornphimoltham, Myung Hee Park

Journal:

International Journal of Cancer

Year:

2004

Language:

english

File:

PDF, 2.33 MB

english, 2004

29

Electrochemical immunosensors for interleukin-6. Comparison of carbon nanotube forest and gold nanoparticle platforms

Bernard S. Munge, Colleen E. Krause, Ruchika Malhotra, Vyomesh Patel, J. Silvio Gutkind, James F. Rusling

Journal:

Electrochemistry Communications

Year:

2009

Language:

english

File:

PDF, 322 KB

english, 2009

30

Immunolocalization of c-Fos and c-Jun in human oral mucosa and in oral squamous cell carcinoma

Suzana Orsini Machado De Sousa, Ricardo Alves Mesquita, Décio Santos Pinto Jr, Silvio Gutkind

Journal:

Journal of Oral Pathology & Medicine

Year:

2002

Language:

english

File:

PDF, 127 KB

english, 2002

31

The PH domain of Ras-GAP is sufficient forin Vitrobinding toβγsubunits of heterotrimeric G proteins

Ningzhi Xu, Omar Coso, Daruka Mahadevan, Antonio De Blasi, Paul K. Goldsmith, William F. Simonds, J. Silvio Gutkind

Journal:

Cellular and Molecular Neurobiology

Year:

1996

Language:

english

File:

PDF, 1.10 MB

english, 1996

32

Classical membrane progesterone receptors in murine mammary carcinomas: agonistic effects of progestins and RU-486 mediating rapid non-genomic effects

María Cecilia Bottino, Juan Pablo Cerliani, Paola Rojas, Sebastián Giulianelli, Rocío Soldati, Carolina Mondillo, María Alicia Gorostiaga, Omar P. Pignataro, Juan Carlos Calvo, J. Silvio Gutkind, Pano

Journal:

Breast Cancer Research and Treatment

Year:

2011

Language:

english

File:

PDF, 1.01 MB

english, 2011

33

MPA-induced gene expression and stromal and parenchymal gene expression profiles in luminal murine mammary carcinomas with different hormonal requirements

Sebastián Giulianelli, Jason I. Herschkowitz, Vyomesh Patel, Caroline A. Lamb, J. Silvio Gutkind, Alfredo Molinolo, Charles M. Perou, Claudia Lanari

Journal:

Breast Cancer Research and Treatment

Year:

2011

Language:

english

File:

PDF, 1.20 MB

english, 2011

34

Accumulation of the SET protein in HEK293T cells and mild oxidative stress: cell survival or death signaling

Andréia M. Leopoldino, Cristiane H. Squarize, Cristiana B. Garcia, Luciana O. Almeida, Cezar R. Pestana, Ana C. M. Polizello, Sérgio A. Uyemura, Eloiza H. Tajara, J. Silvio Gutkind, Carlos Curti

Journal:

Molecular and Cellular Biochemistry

Year:

2012

Language:

english

File:

PDF, 590 KB

english, 2012

35

Microfluidic electrochemical immunoarray for ultrasensitive detection of two cancer biomarker proteins in serum

Bhaskara V. Chikkaveeraiah, Vigneshwaran Mani, Vyomesh Patel, J. Silvio Gutkind, James F. Rusling

Journal:

Biosensors and Bioelectronics

Year:

2011

Language:

english

File:

PDF, 953 KB

english, 2011

36

10.1038/32472

Bais, Carlos, Santomasso, Bianca, Coso, Omar, Arvanitakis, Leandros, Raaka, Elizabeth Geras, Gutkind, J. Silvio, Asch, Adam S., Cesarman, Ethel, Gershengorn, Marvin C., Mesri, Enrique A.

Journal:

Year:

1998

Language:

english

File:

PDF, 1.30 MB

english, 1998

37

10.1038/34193

Mesri, Enrique A., Bais, Carlos, Santomasso, Bianca, Coso, Omar, Arvanitakis, Leandros, Raaka, Elizabeth Geras, Gutkind, J. Silvio, Asch, Adam S., Cesarman, Ethel, Gerhengorn, Marvin C.

Journal:

Year:

1998

Language:

english

File:

PDF, 629 KB

english, 1998

38

10.1038/35010506

Gutkind, J. Silvio, Fukuhara, Shigetomo

Journal:

Nature Cell Biology

Year:

2000

Language:

english

File:

PDF, 101 KB

english, 2000

39

10.1038/35078555

Chiariello, Mario, Marinissen, Maria Julia, Gutkind, J. Silvio

Journal:

Nature Cell Biology

Year:

2001

Language:

english

File:

PDF, 345 KB

english, 2001

40

Ras-dependent activation of MAP kinase pathway mediated by G-protein βγ subunits

Gutkind, J. Silvio, Crespo, Piero, Xu, Ningzhi, Simonds, William F.

Journal:

Year:

1994

File:

PDF, 387 KB

1994

41

Suppression of ceramide-mediated programmed cell death by sphingosine-1-phosphate

Cuvillier, Olivier, Pirianov, Grisha, Kleuser, Burkhard, Vanek, Philip G., Coso, Omar A., Gutkind, J. Silvio, Spiegel, Sarah

Journal:

Year:

1996

File:

PDF, 958 KB

1996

42

Phosphotyrosine-dependent activation of Rac-1 GDP/GTP exchange by the vav proto-oncogene product

Crespo, Piero, Schuebel, Kornel E., Ostrom, Amy A., Gutkind, J. Silvio, Bustelo, Xosé R.

Journal:

Year:

1997

File:

PDF, 1.06 MB

1997

43

Profiling changes in keratinocyte gene expression during wound reepithelialization by laser capture microdissection combined with cDNA array analysis

Pedersen, Tanja X., Leethanakul, Chichadnok, Patel, Vyomesh, Mitola, David, Danø, Keld, Johnsen, Morten, Gutkind, J. Silvio, Bugge, Thomas H.

Journal:

Nature Genetics

Year:

2001

Language:

english

File:

PDF, 35 KB

english, 2001

44

E-cadherin and Hakai: signalling, remodeling or destruction?

Pece, Salvatore, Gutkind, J. Silvio

Journal:

Nature Cell Biology

Year:

2002

Language:

english

File:

PDF, 404 KB

english, 2002

45

VE-cadherin and claudin-5: it takes two to tango

Gavard, Julie, Gutkind, J. Silvio

Journal:

Nature Cell Biology

Year:

2008

Language:

english

File:

PDF, 1.59 MB

english, 2008

46

VEGF controls endothelial-cell permeability by promoting the β-arrestin-dependent endocytosis of VE-cadherin

Gavard, Julie, Gutkind, J. Silvio

Journal:

Nature Cell Biology

Year:

2006

Language:

english

File:

PDF, 2.35 MB

english, 2006

47

The authors' reply

Dorsam, Robert, Gutkind, J. Silvio

Journal:

Nature Reviews Cancer

Year:

2007

Language:

english

File:

PDF, 153 KB

english, 2007

48

Viral hijacking of G-protein-coupled-receptor signalling networks

Sodhi, Akrit, Montaner, Silvia, Gutkind, J. Silvio

Journal:

Nature Reviews Molecular Cell Biology

Year:

2004

Language:

english

File:

PDF, 725 KB

english, 2004

49

PLC-γ activation is required for PDGF-βR-mediated mitogenesis and monocytic differentiation of myeloid progenitor cells

Alimandi, Maurizio, Heidaran, Mohammad A, Gutkind, J Silvio, Zhang, Jiachang, Ellmore, Nelson, Valius, Mindaugas, Kazlauskas, Andrius, Pierce, Jacalyn H, Li, Weiqun

Journal:

Year:

1997

File:

PDF, 1.97 MB

1997

50

Cbl-b, a member of the Sli-1/c-Cbl protein family, inhibits Vav-mediated c-Jun N-terminal kinase activation

Bustelo, Xosé R, Crespo, Piero, López-Barahona, Mónica, Gutkind, J Silvio, Barbacid, Mariano

Journal:

Year:

1997

Language:

english

File:

PDF, 548 KB

english, 1997